Characterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression.

Clouet, Johann; Pot-Vaucel, Marianne; Grimandi, Gaël; Masson, Martial; Lesoeur, Julie; Fellah, Borhane H; Gauthier, Olivier; Fusellier, Marion; Cherel, Yan; Maugars, Yves; Guicheux, Jérôme; Vinatier, Claire

Clouet, Johann; Pot-Vaucel, Marianne; Grimandi, Gaël; Masson, Martial; Lesoeur, Julie; Fellah, Borhane H; Gauthier, Olivier; Fusellier, Marion; Cherel, Yan; Maugars, Yves; Guicheux, Jérôme; Vinatier, Claire.

Affiliation

Clouet J; INSERM (Institut National de la Santé et de la Recherche Médicale) U791, LIOAD, Group Skeletal Tissue Engineering and Physiopathology (STEP), University of Nantes, Nantes F-44042, France.

BMC Musculoskelet Disord ; 12: 147, 2011 Jul 04.

Article in En | MEDLINE | ID: mdl-21726455

Subject(s)

Aging/metabolism; Aging/pathology; Extracellular Matrix Proteins/genetics; Gene Expression Regulation, Developmental/physiology; Intervertebral Disc/metabolism; Animals; Animals, Newborn; Disease Models, Animal; Down-Regulation/genetics; Extracellular Matrix Proteins/biosynthesis; Intervertebral Disc/pathology; Intervertebral Disc/physiology; Magnetic Resonance Imaging/methods; Rabbits; Up-Regulation/genetics

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Full text: 1 Database: MEDLINE Main subject: Aging / Extracellular Matrix Proteins / Gene Expression Regulation, Developmental / Intervertebral Disc Type of study: Prognostic_studies Limits: Animals Language: En Year: 2011 Type: Article

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