The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs.

Tenev, Tencho; Bianchi, Katiuscia; Darding, Maurice; Broemer, Meike; Langlais, Claudia; Wallberg, Fredrik; Zachariou, Anna; Lopez, Juanita; MacFarlane, Marion; Cain, Kelvin; Meier, Pascal

Tenev, Tencho; Bianchi, Katiuscia; Darding, Maurice; Broemer, Meike; Langlais, Claudia; Wallberg, Fredrik; Zachariou, Anna; Lopez, Juanita; MacFarlane, Marion; Cain, Kelvin; Meier, Pascal.

Affiliation

Tenev T; The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, London, UK. tencho.tenev@icr.ac.uk

Mol Cell ; 43(3): 432-48, 2011 Aug 05.

Article in En | MEDLINE | ID: mdl-21737329

Subject(s)

Apoptosis/physiology; Caspase 8/physiology; DNA Damage; Fas-Associated Death Domain Protein/physiology; Inhibitor of Apoptosis Proteins/genetics; Nuclear Pore Complex Proteins/physiology; RNA-Binding Proteins/physiology; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics; CASP8 and FADD-Like Apoptosis Regulating Protein/metabolism; CASP8 and FADD-Like Apoptosis Regulating Protein/physiology; Caspase 8/chemistry; Caspase 8/metabolism; Cell Line, Tumor; Enzyme Activation; Etoposide/pharmacology; Fas-Associated Death Domain Protein/chemistry; Fas-Associated Death Domain Protein/metabolism; Humans; Inhibitor of Apoptosis Proteins/physiology; Ligands; Mitochondria/metabolism; Nuclear Pore Complex Proteins/chemistry; Nuclear Pore Complex Proteins/metabolism; RNA-Binding Proteins/chemistry; RNA-Binding Proteins/metabolism; Signal Transduction

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: DNA Damage / RNA-Binding Proteins / Apoptosis / Nuclear Pore Complex Proteins / Inhibitor of Apoptosis Proteins / Caspase 8 / Fas-Associated Death Domain Protein Limits: Humans Language: En Year: 2011 Type: Article

Fulltext

XML

PubMed Links

Search on Google