Metabolite profiling of recombinant CHO cells: designing tailored feeding regimes that enhance recombinant antibody production.

Sellick, Christopher A; Croxford, Alexandra S; Maqsood, Arfa R; Stephens, Gill; Westerhoff, Hans V; Goodacre, Royston; Dickson, Alan J

Sellick, Christopher A; Croxford, Alexandra S; Maqsood, Arfa R; Stephens, Gill; Westerhoff, Hans V; Goodacre, Royston; Dickson, Alan J.

Affiliation

Sellick CA; Faculty of Life Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.

Biotechnol Bioeng ; 108(12): 3025-31, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21769861

Subject(s)

CHO Cells/chemistry; Culture Media/chemistry; Immunoglobulin G/biosynthesis; Metabolome; Animals; CHO Cells/metabolism; Cell Culture Techniques/methods; Cricetinae; Cricetulus; Immunoglobulin G/genetics; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Technology, Pharmaceutical/methods

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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin G / CHO Cells / Culture Media / Metabolome Limits: Animals Language: En Year: 2011 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin G / CHO Cells / Culture Media / Metabolome Limits: Animals Language: En Year: 2011 Type: Article