Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis.

Wang, David B; Gitcho, Michael A; Kraemer, Brian C; Klein, Ronald L

Wang, David B; Gitcho, Michael A; Kraemer, Brian C; Klein, Ronald L.

Affiliation

Wang DB; Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, USA.

Eur J Neurosci ; 34(8): 1179-88, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21777407

Subject(s)

Amyotrophic Lateral Sclerosis/genetics; Amyotrophic Lateral Sclerosis/therapy; DNA-Binding Proteins/genetics; Disease Models, Animal; Genetic Therapy/methods; Rodentia; Amyotrophic Lateral Sclerosis/pathology; Amyotrophic Lateral Sclerosis/physiopathology; Animals; Animals, Genetically Modified; Gene Transfer Techniques; Genetic Vectors/genetics; Genetic Vectors/therapeutic use; Germ Cells/physiology; Humans; Spinal Cord/pathology; Spinal Cord/physiology; Spinal Cord/physiopathology

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Full text: 1 Database: MEDLINE Main subject: Rodentia / Genetic Therapy / Disease Models, Animal / DNA-Binding Proteins / Amyotrophic Lateral Sclerosis Limits: Animals / Humans Language: En Year: 2011 Type: Article

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