The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis.

Camuesco, D; Rodríguez-Cabezas, M E; Garrido-Mesa, N; Cueto-Sola, M; Bailón, E; Comalada, M; Arribas, B; Merlos, M; Balsa, D; Zarzuelo, A; Janer, G; Xaus, J; Román, J; Gálvez, J

Camuesco, D; Rodríguez-Cabezas, M E; Garrido-Mesa, N; Cueto-Sola, M; Bailón, E; Comalada, M; Arribas, B; Merlos, M; Balsa, D; Zarzuelo, A; Janer, G; Xaus, J; Román, J; Gálvez, J.

Affiliation

Camuesco D; Centro de Investigaciones Biomédicas en Red - Enfermedades Hepáticas y Digestivas (CIBER-EHD), Department of Pharmacology, Center for Biomedical Research, University of Granada, Granada, Spain.

Br J Pharmacol ; 165(3): 729-40, 2012 Feb.

Article in En | MEDLINE | ID: mdl-21790535

Subject(s)

Aminosalicylic Acids/therapeutic use; Anti-Inflammatory Agents/therapeutic use; Aza Compounds/therapeutic use; Azo Compounds/therapeutic use; Colitis/drug therapy; Cytokines/metabolism; Aminosalicylic Acids/pharmacology; Animals; Anti-Inflammatory Agents/pharmacology; Aza Compounds/pharmacology; Azo Compounds/pharmacology; Colitis/chemically induced; Colitis/metabolism; Colon/drug effects; Colon/metabolism; Colon/pathology; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Platelet Activating Factor/antagonists & inhibitors; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid

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Full text: 1 Database: MEDLINE Main subject: Aza Compounds / Azo Compounds / Cytokines / Colitis / Aminosalicylic Acids / Anti-Inflammatory Agents Type of study: Prognostic_studies Limits: Animals Language: En Year: 2012 Type: Article

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