Blood Pressure; Energy Metabolism; Heart Failure/etiology; Hypertrophy, Left Ventricular/complications; Mitochondria, Heart/metabolism; Myocardium/metabolism; Trans-Activators/deficiency; Ventricular Dysfunction, Left/etiology; Aging; Animals; Disease Models, Animal; Disease Progression; Energy Metabolism/genetics; Fatty Acids/metabolism; Gene Expression Regulation; Glucose/metabolism; Heart Failure/diagnostic imaging; Heart Failure/genetics; Heart Failure/metabolism; Heart Failure/physiopathology; Heart Failure/prevention & control; Hexokinase/metabolism; Hypertrophy, Left Ventricular/diagnostic imaging; Hypertrophy, Left Ventricular/physiopathology; Mice; Mice, Knockout; Myocardial Contraction; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Trans-Activators/genetics; Transcription Factors; Ultrasonography; Ventricular Dysfunction, Left/diagnostic imaging; Ventricular Dysfunction, Left/genetics; Ventricular Dysfunction, Left/metabolism; Ventricular Dysfunction, Left/physiopathology; Ventricular Dysfunction, Left/prevention & control; Ventricular Function, Left