ApoB siRNA-induced liver steatosis is resistant to clearance by the loss of fatty acid transport protein 5 (Fatp5).

Ason, Brandon; Castro-Perez, Jose; Tep, Samnang; Stefanni, Alice; Tadin-Strapps, Marija; Roddy, Thomas; Hankemeier, Thomas; Hubbard, Brian; Sachs, Alan B; Michael Flanagan, W; Kuklin, Nelly A; Mitnaul, Lyndon J

Ason, Brandon; Castro-Perez, Jose; Tep, Samnang; Stefanni, Alice; Tadin-Strapps, Marija; Roddy, Thomas; Hankemeier, Thomas; Hubbard, Brian; Sachs, Alan B; Michael Flanagan, W; Kuklin, Nelly A; Mitnaul, Lyndon J.

Affiliation

Ason B; Sirna Therapeutics/Merck & Co. Inc., San Francisco, CA 94158, USA. brandon.ason@amgen.com

Lipids ; 46(11): 991-1003, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21826528

Subject(s)

Apolipoproteins B/genetics; Fatty Acid Transport Proteins/genetics; Fatty Liver/genetics; Animals; Apolipoproteins B/blood; Bile Acids and Salts/metabolism; Cholesterol/blood; Cholesterol, HDL/blood; Female; Gene Expression Profiling; Gene Knockdown Techniques; Lipid Metabolism/genetics; Liver/metabolism; Liver/pathology; Mice; Mice, Inbred C57BL; RNA, Small Interfering; Triglycerides/blood

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Full text: 1 Database: MEDLINE Main subject: Apolipoproteins B / Fatty Acid Transport Proteins / Fatty Liver Limits: Animals Language: En Year: 2011 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Apolipoproteins B / Fatty Acid Transport Proteins / Fatty Liver Limits: Animals Language: En Year: 2011 Type: Article