Extracellular matrix structure and nano-mechanics determine megakaryocyte function.

Malara, Alessandro; Gruppi, Cristian; Pallotta, Isabella; Spedden, Elise; Tenni, Ruggero; Raspanti, Mario; Kaplan, David; Tira, Maria Enrica; Staii, Cristian; Balduini, Alessandra

Malara, Alessandro; Gruppi, Cristian; Pallotta, Isabella; Spedden, Elise; Tenni, Ruggero; Raspanti, Mario; Kaplan, David; Tira, Maria Enrica; Staii, Cristian; Balduini, Alessandra.

Affiliation

Malara A; Department of Biochemistry, Istituto di Ricovero e Cura a Carattere Scientifico San Matteo Foundation, University of Pavia, Pavia, Italy.

Blood ; 118(16): 4449-53, 2011 Oct 20.

Article in En | MEDLINE | ID: mdl-21828129

Subject(s)

Collagen Type I/metabolism; Collagen Type I/ultrastructure; Extracellular Matrix/metabolism; Megakaryocytes/cytology; Cells, Cultured; Collagen Type I/chemistry; Cytoskeleton/metabolism; Cytoskeleton/ultrastructure; Extracellular Matrix/chemistry; Humans; Integrin alpha2beta1/metabolism; Megakaryocytes/metabolism; Megakaryocytes/ultrastructure; Microscopy, Atomic Force; Tensile Strength; Thrombopoiesis

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Full text: 1 Database: MEDLINE Main subject: Megakaryocytes / Collagen Type I / Extracellular Matrix Limits: Humans Language: En Year: 2011 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Megakaryocytes / Collagen Type I / Extracellular Matrix Limits: Humans Language: En Year: 2011 Type: Article