Global IRS-1 phosphorylation analysis in insulin resistance.

Langlais, P; Yi, Z; Finlayson, J; Luo, M; Mapes, R; De Filippis, E; Meyer, C; Plummer, E; Tongchinsub, P; Mattern, M; Mandarino, L J

Langlais, P; Yi, Z; Finlayson, J; Luo, M; Mapes, R; De Filippis, E; Meyer, C; Plummer, E; Tongchinsub, P; Mattern, M; Mandarino, L J.

Affiliation

Langlais P; Center for Metabolic and Vascular Biology, School of Life Science, Arizona State University, ISTB1, 550 E. Orange St, Tempe, AZ 85287, USA.

Diabetologia ; 54(11): 2878-89, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21850561

Subject(s)

Diabetes Mellitus, Type 2/metabolism; Insulin Receptor Substrate Proteins/metabolism; Insulin Resistance; Obesity/metabolism; Protein Processing, Post-Translational; Quadriceps Muscle/metabolism; Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2/drug therapy; Female; Humans; Hypoglycemic Agents/administration & dosage; Hypoglycemic Agents/pharmacology; Hypoglycemic Agents/therapeutic use; Infusions, Intravenous; Insulin/administration & dosage; Insulin/pharmacology; Insulin/therapeutic use; Insulin Receptor Substrate Proteins/chemistry; Male; Middle Aged; Phosphorylation/drug effects; Protein Processing, Post-Translational/drug effects; Serine/chemistry; Serine/metabolism; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine/chemistry; Threonine/metabolism

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Full text: 1 Database: MEDLINE Main subject: Insulin Resistance / Protein Processing, Post-Translational / Diabetes Mellitus, Type 2 / Quadriceps Muscle / Insulin Receptor Substrate Proteins / Obesity Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2011 Type: Article

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