Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia.

Kilic, Ulkan; Yilmaz, Bayram; Ugur, Milas; Yüksel, Adnan; Reiter, Russel J; Hermann, Dirk M; Kilic, Ertugrul

Kilic, Ulkan; Yilmaz, Bayram; Ugur, Milas; Yüksel, Adnan; Reiter, Russel J; Hermann, Dirk M; Kilic, Ertugrul.

Affiliation

Kilic U; Department of Medical Biology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.

J Pineal Res ; 52(2): 228-35, 2012 Mar.

Article in En | MEDLINE | ID: mdl-21913972

Subject(s)

Brain Ischemia/metabolism; Melatonin/metabolism; Receptor, Melatonin, MT1/metabolism; Receptor, Melatonin, MT2/metabolism; Animals; Antioxidants/metabolism; Antioxidants/pharmacology; Blotting, Western; Brain Ischemia/drug therapy; Brain Ischemia/pathology; Male; Melatonin/pharmacology; Mice; Mice, Knockout; Neuroprotective Agents/metabolism; Neuroprotective Agents/pharmacology; Signal Transduction/drug effects; Signal Transduction/physiology

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Full text: 1 Database: MEDLINE Main subject: Brain Ischemia / Receptor, Melatonin, MT1 / Receptor, Melatonin, MT2 / Melatonin Limits: Animals Language: En Year: 2012 Type: Article

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