Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival.

Xu, Lixia; Li, Xiaoxing; Chu, Eagle S H; Zhao, Guijun; Go, Minnie Y Y; Tao, Qian; Jin, Hongchuan; Zeng, Zhirong; Sung, Joseph J Y; Yu, Jun

Xu, Lixia; Li, Xiaoxing; Chu, Eagle S H; Zhao, Guijun; Go, Minnie Y Y; Tao, Qian; Jin, Hongchuan; Zeng, Zhirong; Sung, Joseph J Y; Yu, Jun.

Affiliation

Xu L; Institute of Digestive Disease and Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

Gut ; 61(7): 977-85, 2012 Jul.

Article in En | MEDLINE | ID: mdl-21917650

Subject(s)

Apoptosis/genetics; Biomarkers, Tumor/genetics; Gene Expression Regulation, Neoplastic; Repressor Proteins/genetics; Stomach Neoplasms/genetics; Animals; Biomarkers, Tumor/metabolism; Blotting, Western; Cell Line, Tumor; DNA Methylation; Epigenomics; Female; Genes, Tumor Suppressor; Humans; Male; Mice; Oligonucleotide Array Sequence Analysis; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Stomach Neoplasms/metabolism; Stomach Neoplasms/mortality; Survival Analysis

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Full text: 1 Database: MEDLINE Main subject: Repressor Proteins / Stomach Neoplasms / Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / Apoptosis Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Year: 2012 Type: Article

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