Cholesterol synthesis-related enzyme oxidosqualene cyclase is required to maintain self-renewal in primary erythroid progenitors.

Mejia-Pous, C; Damiola, F; Gandrillon, O

Mejia-Pous, C; Damiola, F; Gandrillon, O.

Affiliation

Mejia-Pous C; Bases Moléculaires de l'Autorenouvellement et de ses Altérations" Group, Université de Lyon, Université Lyon 1, Villeurbanne, Centre de Génétique Moléculaire et Cellulaire, Lyon, France.

Cell Prolif ; 44(5): 441-52, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21951287

Subject(s)

Cholesterol/biosynthesis; Erythroid Precursor Cells/cytology; Erythroid Precursor Cells/metabolism; Intramolecular Transferases/metabolism; Animals; Apoptosis; Base Sequence; Benzophenones/pharmacology; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chickens; Enzyme Inhibitors/pharmacology; Erythroid Precursor Cells/drug effects; Gene Expression Profiling; Hematopoiesis; Homeostasis; In Vitro Techniques; Intramolecular Transferases/antagonists & inhibitors; Intramolecular Transferases/genetics; RNA, Small Interfering/genetics; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Erythroid Precursor Cells / Cholesterol / Intramolecular Transferases Limits: Animals Language: En Year: 2011 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Erythroid Precursor Cells / Cholesterol / Intramolecular Transferases Limits: Animals Language: En Year: 2011 Type: Article