Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents.

Crowell, Susan Ritger; Amin, Shantu G; Anderson, Kim A; Krishnegowda, Gowdahalli; Sharma, Arun K; Soelberg, Jolen J; Williams, David E; Corley, Richard A

Crowell, Susan Ritger; Amin, Shantu G; Anderson, Kim A; Krishnegowda, Gowdahalli; Sharma, Arun K; Soelberg, Jolen J; Williams, David E; Corley, Richard A.

Affiliation

Crowell SR; Biological Monitoring and Modeling Group, Pacific Northwest National Laboratory, Richland, WA 99352, USA. Susan.crowell@pnnl.gov

Toxicol Appl Pharmacol ; 257(3): 365-76, 2011 Dec 15.

Article in En | MEDLINE | ID: mdl-22001385

Subject(s)

Benzo(a)pyrene/pharmacokinetics; Benzopyrenes/pharmacokinetics; Environmental Pollutants/pharmacokinetics; Models, Biological; Administration, Oral; Algorithms; Animals; Benzo(a)pyrene/administration & dosage; Benzo(a)pyrene/chemistry; Benzopyrenes/administration & dosage; Benzopyrenes/chemistry; Environmental Pollutants/administration & dosage; Environmental Pollutants/chemistry; Female; Injections, Intravenous; Mice; Rats; Rats, Sprague-Dawley; Tissue Distribution

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Benzo(a)pyrene / Benzopyrenes / Environmental Pollutants / Models, Biological Limits: Animals Language: En Year: 2011 Type: Article

Fulltext

XML

PubMed Links

Search on Google