Transcription factor c-Maf mediates the TGF-ß-dependent suppression of IL-22 production in T(H)17 cells.

Rutz, Sascha; Noubade, Rajkumar; Eidenschenk, Céline; Ota, Naruhisa; Zeng, Wenwen; Zheng, Yan; Hackney, Jason; Ding, Jiabing; Singh, Harinder; Ouyang, Wenjun

Rutz, Sascha; Noubade, Rajkumar; Eidenschenk, Céline; Ota, Naruhisa; Zeng, Wenwen; Zheng, Yan; Hackney, Jason; Ding, Jiabing; Singh, Harinder; Ouyang, Wenjun.

Affiliation

Rutz S; Department of Immunology, Genentech, South San Francisco, California, USA.

Nat Immunol ; 12(12): 1238-45, 2011 Oct 16.

Article in En | MEDLINE | ID: mdl-22001828

Subject(s)

Interleukins/biosynthesis; Proto-Oncogene Proteins c-maf/metabolism; Th17 Cells/immunology; Transforming Growth Factor beta/pharmacology; Animals; Base Sequence; Basic-Leucine Zipper Transcription Factors/genetics; Basic-Leucine Zipper Transcription Factors/metabolism; Binding Sites/genetics; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation/drug effects; HEK293 Cells; Humans; Interleukins/genetics; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3/genetics; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism; Nucleotide Motifs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-maf/genetics; Receptors, Aryl Hydrocarbon/genetics; Receptors, Aryl Hydrocarbon/metabolism; Th17 Cells/drug effects; Transcription, Genetic; Interleukin-22

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Full text: 1 Database: MEDLINE Main subject: Transforming Growth Factor beta / Interleukins / Proto-Oncogene Proteins c-maf / Th17 Cells Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2011 Type: Article

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