Differential epithelium DNA damage response to ATM and DNA-PK pathway inhibition in human prostate tissue culture.

Zhang, Zhewei; Yang, Zhiming; Jäämaa, Sari; Liu, Hester; Pellakuru, Laxmi G; Iwata, Tsuyoshi; af Hällström, Taija M; De Marzo, Angelo M; Laiho, Marikki

Zhang, Zhewei; Yang, Zhiming; Jäämaa, Sari; Liu, Hester; Pellakuru, Laxmi G; Iwata, Tsuyoshi; af Hällström, Taija M; De Marzo, Angelo M; Laiho, Marikki.

Affiliation

Zhang Z; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Cell Cycle ; 10(20): 3545-53, 2011 Oct 15.

Article in En | MEDLINE | ID: mdl-22030624

Subject(s)

Cell Cycle Proteins/metabolism; DNA Damage; DNA End-Joining Repair/physiology; DNA-Activated Protein Kinase/metabolism; DNA-Binding Proteins/metabolism; Epithelium/metabolism; Protein Serine-Threonine Kinases/metabolism; Signal Transduction/physiology; Tumor Suppressor Proteins/metabolism; Ataxia Telangiectasia Mutated Proteins; Cells, Cultured; Histones/metabolism; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Microscopy, Confocal; Microscopy, Fluorescence; Phosphorylation; Prostate/cytology; Radiation, Ionizing; Repressor Proteins/metabolism; Tripartite Motif-Containing Protein 28

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Full text: 1 Database: MEDLINE Main subject: DNA Damage / Signal Transduction / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Tumor Suppressor Proteins / DNA-Binding Proteins / Epithelium / DNA-Activated Protein Kinase / DNA End-Joining Repair Limits: Humans / Male Language: En Year: 2011 Type: Article

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