Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study.

Joerger, Markus; Burgers, Sjaak A; Baas, Paul; Smit, Egbert F; Haitjema, Tjeerd J; Bard, Martin P L; Doodeman, Valerie D; Smits, Paul H M; Vincent, Andrew; Huitema, Alwin D R; Beijnen, Jos H; Schellens, Jan H M

Joerger, Markus; Burgers, Sjaak A; Baas, Paul; Smit, Egbert F; Haitjema, Tjeerd J; Bard, Martin P L; Doodeman, Valerie D; Smits, Paul H M; Vincent, Andrew; Huitema, Alwin D R; Beijnen, Jos H; Schellens, Jan H M.

Affiliation

Joerger M; Department of Pharmacy and Pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Amsterdam, The Netherlands. markus.joerger@kssg.ch

Cancer ; 118(9): 2466-75, 2012 May 01.

Article in En | MEDLINE | ID: mdl-22031394

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Carboplatin/administration & dosage; Carcinoma, Non-Small-Cell Lung/drug therapy; Carcinoma, Non-Small-Cell Lung/genetics; Cisplatin/administration & dosage; Deoxycytidine/analogs & derivatives; Lung Neoplasms/drug therapy; Lung Neoplasms/genetics; Polymorphism, Genetic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Deoxycytidine/administration & dosage; Disease-Free Survival; Female; Germ Cells; Humans; Lung Neoplasms/mortality; Male; Middle Aged; Prognosis; Treatment Outcome; Gemcitabine

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Full text: 1 Database: MEDLINE Main subject: Polymorphism, Genetic / Antineoplastic Combined Chemotherapy Protocols / Carboplatin / Cisplatin / Carcinoma, Non-Small-Cell Lung / Deoxycytidine / Lung Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2012 Type: Article

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