The discovery of AZD9164, a novel muscarinic M3 antagonist.
Bioorg Med Chem Lett
; 21(24): 7440-6, 2011 Dec 15.
Article
in En
| MEDLINE
| ID: mdl-22047691
ABSTRACT
The optimization of a new series of muscarinic M(3) antagonists is described, leading to the identification of AZD9164 which was progressed into the clinic for evaluation of its potential as a treatment for COPD.
Full text:
1
Database:
MEDLINE
Main subject:
Piperidines
/
Quinuclidines
/
Muscarinic Antagonists
/
Receptor, Muscarinic M3
Limits:
Humans
Language:
En
Year:
2011
Type:
Article