TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia.

Herbaux, Charles; Poulain, Stephanie; Meyer, Claus; Marschalek, Rolf; Renneville, Aline; Fernandes, Jose; Theisen, Olivier; Tricot, Sabine; Simon, Marc; Duthilleul, Patrick; Daudignon, Agnes

Herbaux, Charles; Poulain, Stephanie; Meyer, Claus; Marschalek, Rolf; Renneville, Aline; Fernandes, Jose; Theisen, Olivier; Tricot, Sabine; Simon, Marc; Duthilleul, Patrick; Daudignon, Agnes.

Br J Haematol ; 157(1): 128-31, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22050635

Subject(s)

Chromosomes, Human, Pair 11/genetics; Chromosomes, Human, Pair 17/genetics; DNA Topoisomerases, Type I/genetics; Leukemia, Myeloid, Acute/genetics; Myeloid-Lymphoid Leukemia Protein/genetics; Oncogene Proteins, Fusion/genetics; Translocation, Genetic; Adult; Chromosomes, Human, Pair 11/metabolism; Chromosomes, Human, Pair 17/metabolism; DNA Topoisomerases, Type I/metabolism; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute/blood; Leukemia, Myeloid, Acute/pathology; Male; Middle Aged; Myeloid-Lymphoid Leukemia Protein/metabolism; Oncogene Proteins, Fusion/metabolism

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Full text: 1 Database: MEDLINE Main subject: Translocation, Genetic / Chromosomes, Human, Pair 11 / Chromosomes, Human, Pair 17 / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / DNA Topoisomerases, Type I / Myeloid-Lymphoid Leukemia Protein Limits: Adult / Humans / Male / Middle aged Language: En Year: 2012 Type: Article

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