Androgen receptor signals regulate UDP-glucuronosyltransferases in the urinary bladder: a potential mechanism of androgen-induced bladder carcinogenesis.

Izumi, Koji; Zheng, Yichun; Hsu, Jong-Wei; Chang, Chawnshang; Miyamoto, Hiroshi

Izumi, Koji; Zheng, Yichun; Hsu, Jong-Wei; Chang, Chawnshang; Miyamoto, Hiroshi.

Affiliation

Izumi K; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA.

Mol Carcinog ; 52(2): 94-102, 2013 Feb.

Article in En | MEDLINE | ID: mdl-22086872

Subject(s)

Glucuronosyltransferase/metabolism; Receptors, Androgen/metabolism; Urinary Bladder Neoplasms/metabolism; Urinary Bladder Neoplasms/pathology; Urinary Bladder/metabolism; Aged; Aged, 80 and over; Androgen Antagonists/pharmacology; Animals; Cell Line; Cystectomy; Dihydrotestosterone/pharmacology; Down-Regulation; Female; Flutamide/analogs & derivatives; Flutamide/pharmacology; Follow-Up Studies; Gene Expression Regulation, Enzymologic/drug effects; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Orchiectomy; Receptors, Androgen/genetics; Reference Values; Signal Transduction; UDP-Glucuronosyltransferase 1A9; Urinary Bladder/cytology; Urinary Bladder Neoplasms/surgery

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Full text: 1 Database: MEDLINE Main subject: Urinary Bladder / Urinary Bladder Neoplasms / Receptors, Androgen / Glucuronosyltransferase Type of study: Observational_studies / Prognostic_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Year: 2013 Type: Article

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