Hydroxyureas as noncovalent proteasome inhibitors.

Gallastegui, Nerea; Beck, Philipp; Arciniega, Marcelino; Huber, Robert; Hillebrand, Stefan; Groll, Michael

Gallastegui, Nerea; Beck, Philipp; Arciniega, Marcelino; Huber, Robert; Hillebrand, Stefan; Groll, Michael.

Affiliation

Gallastegui N; Technische Universität München, Lichtenbergstrasse 4, 85747 Garching, Germany.

Angew Chem Int Ed Engl ; 51(1): 247-9, 2012 Jan 02.

Article in En | MEDLINE | ID: mdl-22105886

Subject(s)

Hydroxyurea/chemistry; Protease Inhibitors/chemistry; Proteasome Inhibitors; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Design; Hydrogen Bonding; Proteasome Endopeptidase Complex/metabolism; Protein Structure, Tertiary

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Full text: 1 Database: MEDLINE Main subject: Protease Inhibitors / Proteasome Inhibitors / Hydroxyurea Language: En Year: 2012 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Protease Inhibitors / Proteasome Inhibitors / Hydroxyurea Language: En Year: 2012 Type: Article