Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells.

Novellasdemunt, Laura; Obach, Mercè; Millán-Ariño, Lluís; Manzano, Anna; Ventura, Francesc; Rosa, Jose Luis; Jordan, Albert; Navarro-Sabate, Aurea; Bartrons, Ramon

Novellasdemunt, Laura; Obach, Mercè; Millán-Ariño, Lluís; Manzano, Anna; Ventura, Francesc; Rosa, Jose Luis; Jordan, Albert; Navarro-Sabate, Aurea; Bartrons, Ramon.

Affiliation

Novellasdemunt L; Departament de Ciències Fisiològiques II, IDIBELL (Institut d'Investigacró Biomèdica de Bellvitge), Campus de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.

Biochem J ; 442(2): 345-56, 2012 Mar 01.

Article in En | MEDLINE | ID: mdl-22115192

Subject(s)

Breast Neoplasms/metabolism; Phosphofructokinase-2/metabolism; Progesterone Congeners/pharmacology; Base Sequence; Breast Neoplasms/genetics; Cell Line, Tumor; Enzyme Activation/drug effects; Female; Gene Expression Regulation, Neoplastic/drug effects; Humans; MAP Kinase Signaling System; Norgestrel/pharmacology; Phosphofructokinase-2/genetics; Pregnenediones/pharmacology; Promoter Regions, Genetic; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Neoplasm/genetics; RNA, Neoplasm/metabolism; Receptors, Progesterone/metabolism

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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms / Phosphofructokinase-2 / Progesterone Congeners Limits: Female / Humans Language: En Year: 2012 Type: Article

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