Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human disease.

Ueda, Mitsuharu; Ageyama, Naohide; Nakamura, Shinichiro; Nakamura, Minami; Chambers, James Kenn; Misumi, Yohei; Mizuguchi, Mineyuki; Shinriki, Satoru; Kawahara, Satomi; Tasaki, Masayoshi; Jono, Hirofumi; Obayashi, Konen; Sasaki, Erika; Une, Yumi; Ando, Yukio

Ueda, Mitsuharu; Ageyama, Naohide; Nakamura, Shinichiro; Nakamura, Minami; Chambers, James Kenn; Misumi, Yohei; Mizuguchi, Mineyuki; Shinriki, Satoru; Kawahara, Satomi; Tasaki, Masayoshi; Jono, Hirofumi; Obayashi, Konen; Sasaki, Erika; Une, Yumi; Ando, Yukio.

Affiliation

Ueda M; Department of Diagnostic Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Lab Invest ; 92(3): 474-84, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22184092

Subject(s)

Amyloidosis, Familial/genetics; Chlorocebus aethiops/genetics; Disease Models, Animal; Prealbumin/genetics; Alleles; Amino Acid Sequence; Amyloidosis, Familial/metabolism; Amyloidosis, Familial/pathology; Animals; Chlorocebus aethiops/blood; Heart Function Tests; Humans; Macaca fascicularis/blood; Macaca fascicularis/genetics; Molecular Sequence Data; Mutation; Prealbumin/metabolism; Recombinant Proteins/metabolism; Sequence Alignment; Sequence Homology, Amino Acid

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Full text: 1 Database: MEDLINE Main subject: Prealbumin / Chlorocebus aethiops / Amyloidosis, Familial / Disease Models, Animal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2012 Type: Article

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