All-trans retinoic acid up-regulates Prostaglandin-E Synthase expression in human macrophages.

Mamidi, Srinivas; Hofer, Thomas P J; Hoffmann, Reinhard; Ziegler-Heitbrock, Löms; Frankenberger, Marion

Mamidi, Srinivas; Hofer, Thomas P J; Hoffmann, Reinhard; Ziegler-Heitbrock, Löms; Frankenberger, Marion.

Affiliation

Mamidi S; Clinical Cooperation Group Inflammatory Lung Diseases (Helmholtz Zentrum München and Asklepios Fachkliniken Gauting) Gauting, Robert-Koch Allee 29, D-82131 Gauting, Germany.

Immunobiology ; 217(6): 593-600, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22204820

Subject(s)

Intramolecular Oxidoreductases/metabolism; Macrophages, Alveolar/metabolism; Macrophages/metabolism; RNA, Messenger/biosynthesis; Sarcoidosis, Pulmonary/metabolism; Tretinoin/pharmacology; Bronchoalveolar Lavage; Cells, Cultured; Cyclooxygenase 1/genetics; Cyclooxygenase 1/metabolism; Cyclooxygenase 2/genetics; Cyclooxygenase 2/metabolism; Dinoprostone/metabolism; Dose-Response Relationship, Drug; Gene Expression/drug effects; Humans; Interleukin-13/pharmacology; Intramolecular Oxidoreductases/genetics; Lipopolysaccharides/pharmacology; Macrophages/drug effects; Macrophages/pathology; Macrophages, Alveolar/drug effects; Macrophages, Alveolar/pathology; Oligonucleotide Array Sequence Analysis; Organ Specificity; Prostaglandin H2/metabolism; Prostaglandin-E Synthases; Sarcoidosis, Pulmonary/genetics; Sarcoidosis, Pulmonary/pathology; Signal Transduction/drug effects; Time Factors; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Tretinoin / RNA, Messenger / Macrophages, Alveolar / Sarcoidosis, Pulmonary / Intramolecular Oxidoreductases / Macrophages Limits: Humans Language: En Year: 2012 Type: Article

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