Measurement of parasternal intercostal electromyogram during an infective exacerbation in patients with cystic fibrosis.
Eur Respir J
; 40(4): 977-81, 2012 Oct.
Article
in En
| MEDLINE
| ID: mdl-22267769
ABSTRACT
The parasternal intercostal muscle electromyogram (sEMGpara) is a measure of neural respiratory drive and reflects lung disease severity in stable cystic fibrosis (CF). The aim of the study was to measure sEMGpara in acute infective exacerbations of CF and compare changes in sEMGpara with those in conventional lung function measures. 12 patients with CF admitted to hospital with an acute chest infection were studied. There was a significant reduction in mean ± SD sEMGpara (ΔsEMGpara -38 ± 19%, p<0.001) between admission and discharge. Spirometery also improved significantly from admission to discharge; Δforced expiratory volume in 1 s % predicted 39 ± 30%, p<0.001 and Δvital capacity % pred 22 ± 18%, p<0.001. sEMGpara has potential value as a nonvolitional measure of change in respiratory function in CF.
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Database:
MEDLINE
Main subject:
Respiratory Tract Infections
/
Intercostal Muscles
/
Cystic Fibrosis
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Year:
2012
Type:
Article