&#966;(2)GFP10, a high-intensity fluorophage, enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples.

Jain, Paras; Hartman, Travis E; Eisenberg, Nell; O'Donnell, Max R; Kriakov, Jordan; Govender, Karnishree; Makume, Mantha; Thaler, David S; Hatfull, Graham F; Sturm, A Willem; Larsen, Michelle H; Moodley, Preshnie; Jacobs, William R

φ(2)GFP10, a high-intensity fluorophage, enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples.

Jain, Paras; Hartman, Travis E; Eisenberg, Nell; O'Donnell, Max R; Kriakov, Jordan; Govender, Karnishree; Makume, Mantha; Thaler, David S; Hatfull, Graham F; Sturm, A Willem; Larsen, Michelle H; Moodley, Preshnie; Jacobs, William R.

Affiliation

Jain P; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York, USA.

J Clin Microbiol ; 50(4): 1362-9, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22278833

Subject(s)

Bacteriophages/genetics; Mycobacterium tuberculosis/metabolism; Sputum/microbiology; Tuberculosis, Pulmonary/diagnosis; Antitubercular Agents/pharmacology; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins/biosynthesis; Green Fluorescent Proteins/genetics; Humans; Isoniazid/pharmacology; Kanamycin/pharmacology; Microbial Sensitivity Tests/methods; Mycobacterium tuberculosis/drug effects; Mycobacterium tuberculosis/virology; Ofloxacin/pharmacology; Promoter Regions, Genetic; Recombinant Proteins/biosynthesis; Recombinant Proteins/genetics; Rifampin/pharmacology; Signal-To-Noise Ratio; Tuberculosis, Pulmonary/microbiology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Sputum / Bacteriophages / Tuberculosis, Pulmonary / Mycobacterium tuberculosis Type of study: Diagnostic_studies Limits: Humans Language: En Year: 2012 Type: Article

Fulltext

XML

PubMed Links

Search on Google