Evaluation of novel 99mTc(I)-labeled homobivalent &#945;-melanocyte-stimulating hormone analogs for melanocortin-1 receptor targeting.

Morais, Maurício; Raposinho, Paula D; Oliveira, Maria Cristina; Correia, João D G; Santos, Isabel

Evaluation of novel 99mTc(I)-labeled homobivalent α-melanocyte-stimulating hormone analogs for melanocortin-1 receptor targeting.

Morais, Maurício; Raposinho, Paula D; Oliveira, Maria Cristina; Correia, João D G; Santos, Isabel.

Affiliation

Morais M; Unidade de Ciências Químicas e Radiofarmacêuticas, ITN, Estrada Nacional 10, 2686-953 Sacavém, Portugal.

J Biol Inorg Chem ; 17(4): 491-505, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22286955

Subject(s)

Melanoma, Experimental/diagnosis; Organotechnetium Compounds; Peptides; Receptor, Melanocortin, Type 1/antagonists & inhibitors; Receptor, Melanocortin, Type 1/metabolism; alpha-MSH/analogs & derivatives; Animals; Female; Humans; Melanoma, Experimental/metabolism; Mice; Mice, Inbred C57BL; Molecular Imaging; Organotechnetium Compounds/chemistry; Organotechnetium Compounds/pharmacokinetics; Peptides/chemistry; Peptides/pharmacokinetics; Receptor, Melanocortin, Type 1/chemistry; Tissue Distribution; Tumor Cells, Cultured; alpha-MSH/pharmacokinetics

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Full text: 1 Database: MEDLINE Main subject: Peptides / Melanoma, Experimental / Alpha-MSH / Organotechnetium Compounds / Receptor, Melanocortin, Type 1 Type of study: Evaluation_studies Limits: Animals / Female / Humans Language: En Year: 2012 Type: Article

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