Integrin &#945;1/ß1 and &#945;2/ß1 as a receptor for IgA1 in human glomerular mesangial cells in IgA nephropathy.

Kaneko, Yoshikatsu; Otsuka, Tadashi; Tsuchida, Yohei; Gejyo, Fumitake; Narita, Ichiei

Integrin α1/ß1 and α2/ß1 as a receptor for IgA1 in human glomerular mesangial cells in IgA nephropathy.

Kaneko, Yoshikatsu; Otsuka, Tadashi; Tsuchida, Yohei; Gejyo, Fumitake; Narita, Ichiei.

Affiliation

Kaneko Y; Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 9518510, Japan. kanekoy@med.niigata-u.ac.jp

Int Immunol ; 24(4): 219-32, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22298882

Subject(s)

Glomerular Mesangium/immunology; Glomerulonephritis, IGA/immunology; Immunoglobulin A/immunology; Integrin alpha1beta1/metabolism; Integrin alpha2beta1/metabolism; Mesangial Cells/immunology; Cells, Cultured; Collagen Type IV/metabolism; Dexamethasone/pharmacology; Fluorescein-5-isothiocyanate/pharmacology; Glomerular Mesangium/metabolism; Glomerulonephritis, IGA/metabolism; Glycoside Hydrolases/metabolism; Humans; Immunoglobulin A/chemistry; Immunoglobulin A/metabolism; Manganese/pharmacology; Mesangial Cells/metabolism; Mesangial Cells/pathology; Protein Multimerization; RNA Interference; RNA, Small Interfering; Transforming Growth Factors/pharmacology; Tumor Necrosis Factor-alpha/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin A / Integrin alpha2beta1 / Integrin alpha1beta1 / Mesangial Cells / Glomerular Mesangium / Glomerulonephritis, IGA Limits: Humans Language: En Year: 2012 Type: Article

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