Quantification of the spatial distribution of rectally applied surrogates for microbicide and semen in colon with SPECT and magnetic resonance imaging.

Cao, Ying J; Caffo, Brian S; Fuchs, Edward J; Lee, Linda A; Du, Yong; Li, Liye; Bakshi, Rahul P; Macura, Katarzyna; Khan, Wasif A; Wahl, Richard L; Grohskopf, Lisa A; Hendrix, Craig W

Cao, Ying J; Caffo, Brian S; Fuchs, Edward J; Lee, Linda A; Du, Yong; Li, Liye; Bakshi, Rahul P; Macura, Katarzyna; Khan, Wasif A; Wahl, Richard L; Grohskopf, Lisa A; Hendrix, Craig W.

Affiliation

Cao YJ; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Br J Clin Pharmacol ; 74(6): 1013-22, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22404308

Subject(s)

Cellulose/analogs & derivatives; Colon/metabolism; Gadolinium DTPA/pharmacokinetics; Gadolinium/pharmacokinetics; Glycerol/pharmacokinetics; Pentetic Acid/pharmacokinetics; Phosphates/pharmacokinetics; Propylene Glycols/pharmacokinetics; Technetium Tc 99m Sulfur Colloid/pharmacokinetics; Administration, Rectal; Adult; Anti-Infective Agents/pharmacokinetics; Cellulose/pharmacokinetics; HIV Infections/prevention & control; Homosexuality, Male; Humans; Magnetic Resonance Imaging/methods; Male; Middle Aged; Models, Theoretical; Semen/physiology; Sigmoidoscopy/methods; Tomography, Emission-Computed, Single-Photon/methods

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Full text: 1 Database: MEDLINE Main subject: Phosphates / Propylene Glycols / Technetium Tc 99m Sulfur Colloid / Cellulose / Colon / Gadolinium DTPA / Pentetic Acid / Gadolinium / Glycerol Limits: Adult / Humans / Male / Middle aged Language: En Year: 2012 Type: Article

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