High-risk clonal evolution in chronic B-lymphocytic leukemia: single-center interphase fluorescence in situ hybridization study and review of the literature.

Janssens, Ann; Van Roy, Nadine; Poppe, Bruce; Noens, Lucien; Philippé, Jan; Speleman, Frank; Offner, Fritz

Janssens, Ann; Van Roy, Nadine; Poppe, Bruce; Noens, Lucien; Philippé, Jan; Speleman, Frank; Offner, Fritz.

Affiliation

Janssens A; Department of Haematology, Ghent University Hospital, Ghent, Belgium. Ann.janssens@uz.kuleuven.be

Eur J Haematol ; 89(1): 72-80, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22509718

Subject(s)

Clonal Evolution; Leukemia, Lymphocytic, Chronic, B-Cell/genetics; ADP-ribosyl Cyclase 1/genetics; Adult; Aged; Chromosome Aberrations; Disease Progression; Female; Follow-Up Studies; Gene Expression; Humans; Immunoglobulin Heavy Chains/genetics; Immunoglobulin Variable Region/genetics; In Situ Hybridization, Fluorescence; Leukemia, Lymphocytic, Chronic, B-Cell/mortality; Leukemia, Lymphocytic, Chronic, B-Cell/therapy; Male; Middle Aged; Mutation; Prognosis; Review Literature as Topic; Survival Analysis; Treatment Outcome; ZAP-70 Protein-Tyrosine Kinase/genetics

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Full text: 1 Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Clonal Evolution Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2012 Type: Article

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