Cyclic RGD peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.

Marchini, Mattia; Mingozzi, Michele; Colombo, Raffaele; Guzzetti, Ileana; Belvisi, Laura; Vasile, Francesca; Potenza, Donatella; Piarulli, Umberto; Arosio, Daniela; Gennari, Cesare

Marchini, Mattia; Mingozzi, Michele; Colombo, Raffaele; Guzzetti, Ileana; Belvisi, Laura; Vasile, Francesca; Potenza, Donatella; Piarulli, Umberto; Arosio, Daniela; Gennari, Cesare.

Affiliation

Marchini M; Università degli Studi di Milano, Dipartimento di Chimica Organica e Industriale, Via Venezian, 21, I-20133, Milan, Italy.

Chemistry ; 18(20): 6195-207, 2012 May 14.

Article in En | MEDLINE | ID: mdl-22517378

Subject(s)

Diketopiperazines/chemistry; Models, Molecular; Oligopeptides/chemistry; Peptides, Cyclic/chemistry; Integrin alphaVbeta3/chemistry; Integrin alphaVbeta3/metabolism; Integrins/metabolism; Ligands; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Receptors, Vitronectin/chemistry; Receptors, Vitronectin/metabolism

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Full text: 1 Database: MEDLINE Main subject: Oligopeptides / Peptides, Cyclic / Models, Molecular / Diketopiperazines Language: En Year: 2012 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Oligopeptides / Peptides, Cyclic / Models, Molecular / Diketopiperazines Language: En Year: 2012 Type: Article