The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity.

Vabret, Nicolas; Bailly-Bechet, Marc; Najburg, Valérie; Müller-Trutwin, Michaela; Verrier, Bernard; Tangy, Frédéric

Vabret, Nicolas; Bailly-Bechet, Marc; Najburg, Valérie; Müller-Trutwin, Michaela; Verrier, Bernard; Tangy, Frédéric.

Affiliation

Vabret N; Unité de Génomique Virale et Vaccination, CNRS URA-3015, Institut Pasteur, Paris, France.

PLoS One ; 7(4): e33502, 2012.

Article in En | MEDLINE | ID: mdl-22529893

Subject(s)

HIV-1/genetics; HIV-1/pathogenicity; Interferon Type I/biosynthesis; RNA, Viral/chemistry; Base Composition; Cell Line; Genes, Viral; Genome, Viral; HIV-1/classification; Humans

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Full text: 1 Database: MEDLINE Main subject: RNA, Viral / Interferon Type I / HIV-1 Limits: Humans Language: En Year: 2012 Type: Article

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Full text: 1 Database: MEDLINE Main subject: RNA, Viral / Interferon Type I / HIV-1 Limits: Humans Language: En Year: 2012 Type: Article