Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.

Tantisira, Kelan G; Damask, Amy; Szefler, Stanley J; Schuemann, Brooke; Markezich, Amy; Su, Jessica; Klanderman, Barbara; Sylvia, Jody; Wu, Rongling; Martinez, Fernando; Boushey, Homer A; Chinchilli, Vernon M; Mauger, Dave; Weiss, Scott T; Israel, Elliot

Tantisira, Kelan G; Damask, Amy; Szefler, Stanley J; Schuemann, Brooke; Markezich, Amy; Su, Jessica; Klanderman, Barbara; Sylvia, Jody; Wu, Rongling; Martinez, Fernando; Boushey, Homer A; Chinchilli, Vernon M; Mauger, Dave; Weiss, Scott T; Israel, Elliot.

Affiliation

Tantisira KG; Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA. kelan.tantisira@channing.harvard.edu

Am J Respir Crit Care Med ; 185(12): 1286-91, 2012 Jun 15.

Article in En | MEDLINE | ID: mdl-22538805

Subject(s)

Adrenal Cortex Hormones/therapeutic use; Asthma/drug therapy; Asthma/genetics; Fetal Proteins/genetics; Molecular Targeted Therapy/methods; T-Box Domain Proteins/genetics; Adolescent; Adrenal Cortex Hormones/genetics; Adult; Alleles; Child; Child, Preschool; Female; Fetal Proteins/drug effects; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Prognosis; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; T-Box Domain Proteins/drug effects; Treatment Outcome; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Asthma / Adrenal Cortex Hormones / T-Box Domain Proteins / Molecular Targeted Therapy / Fetal Proteins Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male / Middle aged Language: En Year: 2012 Type: Article

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