Pharmacokinetics of lansoprazole and its main metabolites after single intravenous doses in healthy Chinese subjects.

Zhang, Dan; Yang, Man; Liu, Man; Zhang, Yanan; Wang, Xiaolin; Xiao, Xue; Liu, Huichen

Zhang, Dan; Yang, Man; Liu, Man; Zhang, Yanan; Wang, Xiaolin; Xiao, Xue; Liu, Huichen.

Affiliation

Zhang D; Department of Clinical Pharmacology, Aerospace Center Hospital, Beijing, PR China.

Xenobiotica ; 42(11): 1156-62, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22612620

Subject(s)

2-Pyridinylmethylsulfinylbenzimidazoles/pharmacokinetics; Anti-Ulcer Agents/pharmacokinetics; Aryl Hydrocarbon Hydroxylases/genetics; 2-Pyridinylmethylsulfinylbenzimidazoles/administration & dosage; 2-Pyridinylmethylsulfinylbenzimidazoles/blood; Adult; Anti-Ulcer Agents/administration & dosage; Anti-Ulcer Agents/blood; Aryl Hydrocarbon Hydroxylases/metabolism; Asian People; China; Cross-Over Studies; Cytochrome P-450 CYP2C19; Female; Humans; Injections, Intravenous; Lansoprazole; Male; Polymorphism, Genetic; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Aryl Hydrocarbon Hydroxylases / 2-Pyridinylmethylsulfinylbenzimidazoles / Anti-Ulcer Agents Type of study: Clinical_trials Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: En Year: 2012 Type: Article

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