DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes.

Rose, J; Söder, S; Skhirtladze, C; Schmitz, N; Gebhard, P M; Sesselmann, S; Aigner, T

Rose, J; Söder, S; Skhirtladze, C; Schmitz, N; Gebhard, P M; Sesselmann, S; Aigner, T.

Affiliation

Rose J; Department of Orthopaedic and Trauma Surgery, University of Cologne, Joseph-Stelzmann-Str. 9, 50924 Cologne, Germany.

Osteoarthritis Cartilage ; 20(9): 1020-8, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22659602

Subject(s)

Cartilage, Articular/metabolism; Cellular Senescence/genetics; Chondrocytes/metabolism; Gene Expression; Osteoarthritis, Knee/genetics; Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA Damage; Flow Cytometry; Humans; Middle Aged; Osteoarthritis, Knee/metabolism; S100 Proteins/metabolism; Vimentin/metabolism

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Full text: 1 Database: MEDLINE Main subject: Cartilage, Articular / Gene Expression / Cellular Senescence / Chondrocytes / Osteoarthritis, Knee Type of study: Observational_studies Limits: Adult / Aged / Aged80 / Humans / Middle aged Language: En Year: 2012 Type: Article

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