An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis.

Lamprecht, Dirk A; Muneri, Ndivhuwo O; Eastwood, Hayden; Naidoo, Kevin J; Strauss, Erick; Jardine, Anwar

Lamprecht, Dirk A; Muneri, Ndivhuwo O; Eastwood, Hayden; Naidoo, Kevin J; Strauss, Erick; Jardine, Anwar.

Affiliation

Lamprecht DA; Department of Biochemistry, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Org Biomol Chem ; 10(27): 5278-88, 2012 Jul 21.

Article in En | MEDLINE | ID: mdl-22678300

Subject(s)

Amidohydrolases/chemistry; Bacterial Proteins/chemistry; Cysteine/biosynthesis; Glycopeptides/biosynthesis; Inositol/biosynthesis; Mycobacterium tuberculosis/enzymology; Amidohydrolases/metabolism; Bacterial Proteins/metabolism; Biocatalysis; Catalytic Domain; Cysteine/chemistry; Glycopeptides/chemistry; Inositol/chemistry; Models, Molecular; Substrate Specificity

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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Glycopeptides / Cysteine / Amidohydrolases / Inositol / Mycobacterium tuberculosis Type of study: Prognostic_studies Language: En Year: 2012 Type: Article

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