Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.

Asano, Satoshi; Kitatani, Kazuyuki; Taniguchi, Makoto; Hashimoto, Mayumi; Zama, Kota; Mitsutake, Susumu; Igarashi, Yasuyuki; Takeya, Hiroyuki; Kigawa, Junzo; Hayashi, Akira; Umehara, Hisanori; Okazaki, Toshiro

Asano, Satoshi; Kitatani, Kazuyuki; Taniguchi, Makoto; Hashimoto, Mayumi; Zama, Kota; Mitsutake, Susumu; Igarashi, Yasuyuki; Takeya, Hiroyuki; Kigawa, Junzo; Hayashi, Akira; Umehara, Hisanori; Okazaki, Toshiro.

Affiliation

Asano S; Division of Clinical Laboratory Medicine, Tottori University, Yonago, Japan.

Mol Cell Biol ; 32(16): 3242-52, 2012 Aug.

Article in En | MEDLINE | ID: mdl-22688512

Subject(s)

Chemokine CXCL12/metabolism; Gene Expression Regulation; Receptors, CXCR4/metabolism; Sphingomyelins/metabolism; Animals; Cell Movement; Chemotaxis; Extracellular Signal-Regulated MAP Kinases/metabolism; Fibroblasts/cytology; Humans; Lipids/chemistry; Membrane Microdomains/chemistry; Mice; Models, Biological; Signal Transduction

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Full text: 1 Database: MEDLINE Main subject: Sphingomyelins / Gene Expression Regulation / Receptors, CXCR4 / Chemokine CXCL12 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2012 Type: Article

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