E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis.

Wolyniec, Kamil; Shortt, Jake; de Stanchina, Elisa; Levav-Cohen, Yaara; Alsheich-Bartok, Osnat; Louria-Hayon, Igal; Corneille, Vincent; Kumar, Beena; Woods, Simone J; Opat, Stephen; Johnstone, Ricky W; Scott, Clare L; Segal, David; Pandolfi, Pier Paolo; Fox, Stephen; Strasser, Andreas; Jiang, Yong-Hui; Lowe, Scott W; Haupt, Sue; Haupt, Ygal

Wolyniec, Kamil; Shortt, Jake; de Stanchina, Elisa; Levav-Cohen, Yaara; Alsheich-Bartok, Osnat; Louria-Hayon, Igal; Corneille, Vincent; Kumar, Beena; Woods, Simone J; Opat, Stephen; Johnstone, Ricky W; Scott, Clare L; Segal, David; Pandolfi, Pier Paolo; Fox, Stephen; Strasser, Andreas; Jiang, Yong-Hui; Lowe, Scott W; Haupt, Sue; Haupt, Ygal.

Affiliation

Wolyniec K; Research Division, The Peter MacCallum Cancer Centre, East Melbourne, 3002 Victoria, Australia.

Blood ; 120(4): 822-32, 2012 Jul 26.

Article in En | MEDLINE | ID: mdl-22689861

Subject(s)

Burkitt Lymphoma/pathology; Cellular Senescence; Lymphoma, Large B-Cell, Diffuse/pathology; Nuclear Proteins/metabolism; Proto-Oncogene Proteins c-myc/physiology; Transcription Factors/metabolism; Tumor Suppressor Proteins/metabolism; Ubiquitin-Protein Ligases/metabolism; Animals; Apoptosis; Burkitt Lymphoma/metabolism; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Lymphoma, Large B-Cell, Diffuse/metabolism; Mice; Mice, Inbred C57BL; Mice, Transgenic; Promyelocytic Leukemia Protein; Proteasome Endopeptidase Complex; Ubiquitin/metabolism

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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Proto-Oncogene Proteins c-myc / Lymphoma, Large B-Cell, Diffuse / Burkitt Lymphoma / Cellular Senescence / Tumor Suppressor Proteins / Ubiquitin-Protein Ligases Limits: Animals / Humans Language: En Year: 2012 Type: Article

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