Inhibition of erythropoiesis by Smad6 in human cord blood hematopoietic stem cells.

Kang, Young-Ju; Shin, Ji-woong; Yoon, Jeong-Hwan; Oh, Il-Hwan; Lee, Soon-Pyo; Kim, Suk-Young; Park, Seok Hee; Mamura, Mizuko

Kang, Young-Ju; Shin, Ji-woong; Yoon, Jeong-Hwan; Oh, Il-Hwan; Lee, Soon-Pyo; Kim, Suk-Young; Park, Seok Hee; Mamura, Mizuko.

Affiliation

Kang YJ; Laboratory of Immunology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.

Biochem Biophys Res Commun ; 423(4): 750-6, 2012 Jul 13.

Article in En | MEDLINE | ID: mdl-22705548

Subject(s)

Erythropoiesis/genetics; Gene Expression Regulation; Hematopoietic Stem Cells/cytology; Smad6 Protein/metabolism; Antigens, CD34/analysis; Bone Morphogenetic Protein 2/genetics; Bone Morphogenetic Protein 4/genetics; Bone Morphogenetic Protein 6/genetics; Bone Morphogenetic Protein 7/genetics; Bone Morphogenetic Protein Receptors, Type I/genetics; Cells, Cultured; Fetal Blood/cytology; GATA2 Transcription Factor/genetics; Gene Knockdown Techniques; Hematopoietic Stem Cells/metabolism; Humans; Kruppel-Like Transcription Factors/genetics; Promoter Regions, Genetic; Smad6 Protein/genetics; Transcription, Genetic

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Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / Gene Expression Regulation / Erythropoiesis / Smad6 Protein Limits: Humans Language: En Year: 2012 Type: Article

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