Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells.

Chen, Yulin; Li, Dan; Wang, Dapeng; Liu, Xuefeng; Yin, Ning; Song, Yongmei; Lu, Shih Hsin; Ju, Zhenyu; Zhan, Qimin

Chen, Yulin; Li, Dan; Wang, Dapeng; Liu, Xuefeng; Yin, Ning; Song, Yongmei; Lu, Shih Hsin; Ju, Zhenyu; Zhan, Qimin.

Affiliation

Chen Y; State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

J Cell Biochem ; 113(12): 3643-52, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22711554

Subject(s)

DNA Damage; DNA Repair; DNA, Neoplasm/analysis; Esophageal Neoplasms/pathology; Neoplastic Stem Cells/pathology; Apoptosis; Benzimidazoles; Cell Line, Tumor; Cell Survival; Cisplatin/pharmacology; Coculture Techniques; DNA, Neoplasm/genetics; Drug Resistance, Neoplasm; ErbB Receptors/genetics; ErbB Receptors/metabolism; Esophageal Neoplasms/genetics; Flow Cytometry; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Mutagenicity Tests/methods; Neoplastic Stem Cells/drug effects; Phenotype; Phosphorylation; STAT3 Transcription Factor/genetics; STAT3 Transcription Factor/metabolism; Tumor Stem Cell Assay; Ultraviolet Rays

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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / DNA Damage / DNA, Neoplasm / Esophageal Neoplasms / DNA Repair Limits: Humans Language: En Year: 2012 Type: Article

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