p38Î³ and p38Î´ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation.

Risco, Ana; del Fresno, Carlos; Mambol, Agnes; Alsina-Beauchamp, Dayanira; MacKenzie, Kirsty F; Yang, Huei-Ting; Barber, Domingo F; Morcelle, Carmen; Arthur, J Simon C; Ley, Steven C; Ardavin, Carlos; Cuenda, Ana

Risco, Ana; del Fresno, Carlos; Mambol, Agnes; Alsina-Beauchamp, Dayanira; MacKenzie, Kirsty F; Yang, Huei-Ting; Barber, Domingo F; Morcelle, Carmen; Arthur, J Simon C; Ley, Steven C; Ardavin, Carlos; Cuenda, Ana.

Affiliation

Risco A; Department of Immunology and Oncology, Centro Nacional de Biotecnología/Consejo Superior de Investigaciones Cientificas (CNB/CSIC), 28049-Madrid, Spain.

Proc Natl Acad Sci U S A ; 109(28): 11200-5, 2012 Jul 10.

Article in En | MEDLINE | ID: mdl-22733747

Subject(s)

Cytokines/metabolism; Gene Expression Regulation; Mitogen-Activated Protein Kinase 13/chemistry; Toll-Like Receptor 4/metabolism; p38 Mitogen-Activated Protein Kinases/chemistry; Animals; Cattle; Cells, Cultured; Culture Media, Conditioned/pharmacology; Gene Deletion; Humans; Immunity, Innate; MAP Kinase Signaling System; Macrophages/metabolism; Mice; Mitogen-Activated Protein Kinase 3/metabolism; Protein Isoforms; Shock, Septic/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation / Cytokines / P38 Mitogen-Activated Protein Kinases / Mitogen-Activated Protein Kinase 13 / Toll-Like Receptor 4 Limits: Animals / Humans Language: En Year: 2012 Type: Article

Fulltext

XML

PubMed Links

Search on Google