Placement of an elastic biodegradable cardiac patch on a subacute infarcted heart leads to cellularization with early developmental cardiomyocyte characteristics.

Fujimoto, Kazuro L; Tobita, Kimimasa; Guan, Jianjun; Hashizume, Ryotaro; Takanari, Keisuke; Alfieri, Christina M; Yutzey, Katherine E; Wagner, William R

Fujimoto, Kazuro L; Tobita, Kimimasa; Guan, Jianjun; Hashizume, Ryotaro; Takanari, Keisuke; Alfieri, Christina M; Yutzey, Katherine E; Wagner, William R.

Affiliation

Fujimoto KL; Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15219, USA.

J Card Fail ; 18(7): 585-95, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22748493

Subject(s)

Biocompatible Materials/administration & dosage; Myocardial Infarction/pathology; Myocardial Infarction/therapy; Myocardium/metabolism; Myocardium/pathology; Actins/metabolism; Animals; Animals, Newborn; Connexin 43/metabolism; Echocardiography; Elasticity; Female; Fetus; Fibrosis; GATA4 Transcription Factor/genetics; GATA4 Transcription Factor/metabolism; Heart/embryology; Heart Ventricles/pathology; Homeobox Protein Nkx-2.5; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Immunohistochemistry; Microscopy, Electron; Polytetrafluoroethylene; Polyurethanes; RNA, Messenger/metabolism; Rats; Regeneration; Transcription Factors/genetics; Transcription Factors/metabolism; Troponin T/metabolism; Ventricular Remodeling

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Full text: 1 Database: MEDLINE Main subject: Biocompatible Materials / Myocardial Infarction / Myocardium Limits: Animals Language: En Year: 2012 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Biocompatible Materials / Myocardial Infarction / Myocardium Limits: Animals Language: En Year: 2012 Type: Article