The PavA-like fibronectin-binding protein of Enterococcus faecalis, EfbA, is important for virulence in a mouse model of ascending urinary tract infection.

Torelli, Riccardo; Serror, Pascale; Bugli, Francesca; Paroni Sterbini, Francesco; Florio, Ada Rita; Stringaro, Annarita; Colone, Marisa; De Carolis, Elena; Martini, Cecilia; Giard, Jean-Christophe; Sanguinetti, Maurizio; Posteraro, Brunella

Torelli, Riccardo; Serror, Pascale; Bugli, Francesca; Paroni Sterbini, Francesco; Florio, Ada Rita; Stringaro, Annarita; Colone, Marisa; De Carolis, Elena; Martini, Cecilia; Giard, Jean-Christophe; Sanguinetti, Maurizio; Posteraro, Brunella.

Affiliation

Torelli R; Institute of Microbiology, Università Cattolica del Sacro Cuore, Largo F Vito, 1 00168 Rome, Italy.

J Infect Dis ; 206(6): 952-60, 2012 Sep 15.

Article in En | MEDLINE | ID: mdl-22782954

Subject(s)

Bacterial Proteins/metabolism; Enterococcus faecalis/pathogenicity; Gram-Positive Bacterial Infections/microbiology; Urinary Tract Infections/microbiology; Animals; Bacterial Adhesion; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Enterococcus faecalis/metabolism; Enzyme-Linked Immunosorbent Assay/methods; Female; Fibronectins/metabolism; Fluorescent Antibody Technique; Gene Deletion; Gene Expression Regulation, Bacterial/physiology; Immunoblotting; Membrane Proteins/metabolism; Mice; Microscopy, Immunoelectron; Protein Binding; Recombinant Proteins; Virulence

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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Urinary Tract Infections / Gram-Positive Bacterial Infections / Enterococcus faecalis Limits: Animals Language: En Year: 2012 Type: Article

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