Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam.

Ochoa-Sanchez, Rafael; Rainer, Quentin; Comai, Stefano; Spadoni, Gilberto; Bedini, Annalida; Rivara, Silvia; Fraschini, Franco; Mor, Marco; Tarzia, Giorgio; Gobbi, Gabriella

Ochoa-Sanchez, Rafael; Rainer, Quentin; Comai, Stefano; Spadoni, Gilberto; Bedini, Annalida; Rivara, Silvia; Fraschini, Franco; Mor, Marco; Tarzia, Giorgio; Gobbi, Gabriella.

Affiliation

Ochoa-Sanchez R; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University and McGill University Health Center, Montreal, QC, Canada.

Prog Neuropsychopharmacol Biol Psychiatry ; 39(2): 318-25, 2012 Dec 03.

Article in En | MEDLINE | ID: mdl-22789661

Subject(s)

Acetamides/pharmacology; Aniline Compounds/pharmacology; Diazepam/pharmacology; Melatonin/pharmacology; Receptor, Melatonin, MT2/agonists; Acetamides/antagonists & inhibitors; Aniline Compounds/antagonists & inhibitors; Animals; Anti-Anxiety Agents/antagonists & inhibitors; Anti-Anxiety Agents/pharmacology; Anti-Anxiety Agents/therapeutic use; Anxiety/drug therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Partial Agonism; Feeding Behavior/drug effects; Male; Maze Learning/drug effects; Melatonin/antagonists & inhibitors; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT2/antagonists & inhibitors; Tetrahydronaphthalenes/pharmacology; Tryptamines/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Receptor, Melatonin, MT2 / Diazepam / Aniline Compounds / Acetamides / Melatonin Limits: Animals Language: En Year: 2012 Type: Article

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