Soluble &#945;-synuclein is a novel modulator of Alzheimer's disease pathophysiology.

Larson, Megan E; Sherman, Mathew A; Greimel, Susan; Kuskowski, Michael; Schneider, Julie A; Bennett, David A; Lesné, Sylvain E

Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.

Larson, Megan E; Sherman, Mathew A; Greimel, Susan; Kuskowski, Michael; Schneider, Julie A; Bennett, David A; Lesné, Sylvain E.

Affiliation

Larson ME; Department of Neuroscience, N. Bud Grossman Center for Memory Research and Care, and Institute for Translational Neuroscience, University of Minnesota, Minneapolis, Minnesota 55414, USA.

J Neurosci ; 32(30): 10253-66, 2012 Jul 25.

Article in En | MEDLINE | ID: mdl-22836259

Subject(s)

Alzheimer Disease/metabolism; Cognitive Dysfunction/metabolism; Neurons/metabolism; Temporal Lobe/metabolism; alpha-Synuclein/metabolism; Aged; Aged, 80 and over; Alzheimer Disease/pathology; Amyloid beta-Peptides/metabolism; Animals; Cognitive Dysfunction/pathology; Disease Models, Animal; Humans; Maze Learning; Mice; Mice, Transgenic; Nerve Fibers, Unmyelinated/metabolism; Nerve Fibers, Unmyelinated/pathology; Neurons/pathology; Neuropsychological Tests; Presenilin-1/metabolism; Temporal Lobe/pathology; tau Proteins/metabolism

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Full text: 1 Database: MEDLINE Main subject: Temporal Lobe / Alpha-Synuclein / Alzheimer Disease / Cognitive Dysfunction / Neurons Limits: Aged / Aged80 / Animals / Humans Language: En Year: 2012 Type: Article

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