1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects; Apoptosis/drug effects; Forkhead Transcription Factors/metabolism; MPTP Poisoning/metabolism; Nerve Tissue Proteins/metabolism; Neurotoxins/adverse effects; Parkinson Disease, Secondary/metabolism; Sirtuin 2/metabolism; Striatonigral Degeneration/metabolism; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/pharmacology; Acetylation/drug effects; Animals; Apoptosis/genetics; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Forkhead Box Protein O3; Forkhead Transcription Factors/genetics; MPTP Poisoning/genetics; MPTP Poisoning/pathology; MPTP Poisoning/therapy; Membrane Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins/genetics; Neurotoxins/pharmacology; Parkinson Disease, Secondary/chemically induced; Parkinson Disease, Secondary/genetics; Parkinson Disease, Secondary/pathology; Parkinson Disease, Secondary/therapy; Proto-Oncogene Proteins; Sirtuin 2/genetics; Striatonigral Degeneration/chemically induced; Striatonigral Degeneration/genetics; Striatonigral Degeneration/mortality; Striatonigral Degeneration/therapy; Substantia Nigra/metabolism; Substantia Nigra/pathology