Increased mitotic rate coincident with transient telomere lengthening resulting from pim-1 overexpression in cardiac progenitor cells.

Cottage, Christopher T; Neidig, Lauren; Sundararaman, Balaji; Din, Shabana; Joyo, Anya Y; Bailey, Brandi; Gude, Natalie; Hariharan, Nirmala; Sussman, Mark A

Cottage, Christopher T; Neidig, Lauren; Sundararaman, Balaji; Din, Shabana; Joyo, Anya Y; Bailey, Brandi; Gude, Natalie; Hariharan, Nirmala; Sussman, Mark A.

Affiliation

Cottage CT; San Diego State Heart Institute, San Diego State University, San Diego, California, USA.

Stem Cells ; 30(11): 2512-22, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22915504

Subject(s)

Mitosis; Myocardium/cytology; Proto-Oncogene Proteins c-pim-1/metabolism; Stem Cells/physiology; Telomere Homeostasis; Animals; Cardiotoxins/pharmacology; Cell Proliferation; Cell Survival; Cells, Cultured; Doxorubicin/pharmacology; Enzyme Activation; Gene Expression; Green Fluorescent Proteins/biosynthesis; Green Fluorescent Proteins/genetics; Mice; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc/antagonists & inhibitors; Proto-Oncogene Proteins c-myc/metabolism; Proto-Oncogene Proteins c-pim-1/genetics; Regenerative Medicine; Stem Cells/enzymology; Stem Cells/metabolism; Telomerase/metabolism; Telomere Homeostasis/drug effects; Thiazoles/pharmacology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Stem Cells / Proto-Oncogene Proteins c-pim-1 / Telomere Homeostasis / Mitosis / Myocardium Limits: Animals Language: En Year: 2012 Type: Article

Fulltext

XML

PubMed Links

Search on Google