Chemical perturbation of secondary metabolism demonstrates important links to primary metabolism.

Craney, Arryn; Ozimok, Cory; Pimentel-Elardo, Sheila Marie; Capretta, Alfredo; Nodwell, Justin R.

Affiliation

Craney A; Michael Degroote Institute for Infectious Disease Research, McMaster University, 1280 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.

Chem Biol ; 19(8): 1020-7, 2012 Aug 24.

Article in En | MEDLINE | ID: mdl-22921069

Subject(s)

Actinobacteria/metabolism; Fatty Acids/biosynthesis; Anthraquinones/chemistry; Anthraquinones/metabolism; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/metabolism; Chromatography, High Pressure Liquid; Mass Spectrometry; Prodigiosin/analogs & derivatives; Prodigiosin/chemistry; Prodigiosin/metabolism; Small Molecule Libraries/chemistry; Small Molecule Libraries/metabolism; Spectrophotometry; Streptomyces coelicolor/metabolism