Nâ(w) -propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses.

Beamer, Edward; Otahal, Jakub; Sills, Graeme J; Thippeswamy, Thimmasettappa

Nâ(w) -propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses.

Beamer, Edward; Otahal, Jakub; Sills, Graeme J; Thippeswamy, Thimmasettappa.

Affiliation

Beamer E; Institute of Ageing and Chronic Disease, Faculty of Health and Life Sciences, University of Liverpool, 4th floor Room 4.306, UCD Duncan Building, Daulby Street, Liverpool L69 3GA, UK.

Eur J Neurosci ; 36(9): 3194-203, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22943535

Subject(s)

Arginine/analogs & derivatives; Brain Waves/drug effects; Status Epilepticus/drug therapy; Animals; Arginine/therapeutic use; Dentate Gyrus/chemistry; Dentate Gyrus/cytology; Dentate Gyrus/physiopathology; Diazepam/pharmacology; Disease Models, Animal; Gliosis/drug therapy; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos/analysis; Seizures/chemically induced; Seizures/drug therapy; Seizures/physiopathology; Status Epilepticus/chemically induced; Status Epilepticus/physiopathology; Synapses/drug effects; Synaptophysin/analysis; Telemetry

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Full text: 1 Database: MEDLINE Main subject: Arginine / Status Epilepticus / Brain Waves Type of study: Prognostic_studies Limits: Animals Language: En Year: 2012 Type: Article

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