Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy.

Zoja, Carla; Garcia, Pablo Bautista; Rota, Cinzia; Conti, Sara; Gagliardini, Elena; Corna, Daniela; Zanchi, Cristina; Bigini, Paolo; Benigni, Ariela; Remuzzi, Giuseppe; Morigi, Marina

Zoja, Carla; Garcia, Pablo Bautista; Rota, Cinzia; Conti, Sara; Gagliardini, Elena; Corna, Daniela; Zanchi, Cristina; Bigini, Paolo; Benigni, Ariela; Remuzzi, Giuseppe; Morigi, Marina.

Affiliation

Zoja C; Mario Negri Institute for Pharmacological Research, Centro Anna Maria Astori, Science and Technology Park Km Rosso, Via Stezzano, 87-24126 Bergamo, Italy. carlamaria.zoja@marionegri.it

Am J Physiol Renal Physiol ; 303(9): F1370-81, 2012 Nov 01.

Article in En | MEDLINE | ID: mdl-22952284

Subject(s)

Kidney Diseases/pathology; Kidney Diseases/physiopathology; Kidney/physiology; Mesenchymal Stem Cell Transplantation; Podocytes/physiology; Regeneration/physiology; Stem Cells/physiology; Adaptor Proteins, Signal Transducing/metabolism; Animals; Apoptosis/physiology; Cell Count; Cell Movement/physiology; Coculture Techniques; Cytoskeletal Proteins/metabolism; Disease Models, Animal; Doxorubicin/adverse effects; Kidney/pathology; Kidney Diseases/chemically induced; Male; Membrane Proteins/metabolism; Podocytes/pathology; Rats; Rats, Inbred Lew; Stem Cells/pathology; Treatment Outcome; Vascular Endothelial Growth Factor A/metabolism

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Full text: 1 Database: MEDLINE Main subject: Regeneration / Stem Cells / Mesenchymal Stem Cell Transplantation / Podocytes / Kidney / Kidney Diseases Type of study: Prognostic_studies Limits: Animals Language: En Year: 2012 Type: Article

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