After TGN1412: recent developments in cytokine release assays.

Stebbings, R; Eastwood, D; Poole, S; Thorpe, R

Stebbings, R; Eastwood, D; Poole, S; Thorpe, R.

Affiliation

Stebbings R; Biotherapeutics Group, NIBSC, Potters Bar, Hertfordshire EN6 3QG, UK. richard.stebbings@nibsc.hpa.org.uk

J Immunotoxicol ; 10(1): 75-82, 2013.

Article in En | MEDLINE | ID: mdl-22967038

Subject(s)

Antibodies, Monoclonal, Humanized/adverse effects; CD4-Positive T-Lymphocytes/drug effects; Cytotoxicity Tests, Immunologic; Interleukin-2/immunology; Animals; Antibodies, Immobilized; CD28 Antigens/immunology; CD4-Positive T-Lymphocytes/immunology; Clinical Trials, Phase I as Topic; Coculture Techniques; Cytokines/immunology; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelial Cells; Humans; Immunologic Memory/drug effects; Inflammation/etiology; Macaca fascicularis; Predictive Value of Tests; Treatment Failure

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Full text: 1 Database: MEDLINE Main subject: Cytotoxicity Tests, Immunologic / CD4-Positive T-Lymphocytes / Interleukin-2 / Antibodies, Monoclonal, Humanized Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Year: 2013 Type: Article

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